$300,000

Houston Methodist Neurological Institute

In December 2023, we funded Dr. Stanley Appel’s study of Extracellular Vesicles Derived From Ex Vivo Expanded Regulatory T Cells Modulate In Vitro and In Vivo Inflammation.  Neuroinflammation is known to exacerbate motor neuron dysfunction, which can ultimately lead to motor neuron death. This study supports the therapeutic potential of expanded Treg Extracellular Vesicles to suppress pro-inflammatory response, support motor neuron life, and slow the progression of human disease.

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